Young women with breast cancer who are on Arimidex...? - breast cancer aromatase inhibitor
I was on Zoladex and Arimidex (aromatase inhibitor) for two years because I cancer hormone receptor-positive and positive HER2neu.
Unfortunately, I experienced a total change of character. I became very depressed and even aggressive. At first I thought he dealt with my diagnosis of cancer, so I had counseling, but he really ran everything very well under the circumstances.
I spoke to my oncologist and now I'm on a break Arimidex (I'll take still pictures Zoladex). And I realized that change immediately. Not only that, I feel much more mentally stable, but bone and muscle pain are also terrible. But now I'm scared because I feel insecure ...
Any other person who is against women going through menopause, had problems with Arimidex or an aromatase inhibitor as well? In response to this situation?
Please note that due to my being HER2neu BC + + + I am not able to go tamoxifen.
Sunday, January 17, 2010
Breast Cancer Aromatase Inhibitor Young Women With Breast Cancer Who Are On Arimidex...?
2 comments:
I am a little confused by your question. Aromatase inhibitors are only in postmenopausal women - hope you are menopausal or aromatase inhibitors do not work. Tamoxifen is indicated for women before menopause and can be used with HER-2 neu + patients. Have you ever been on Herceptin? This is a targeted therapy for women who are HER-2 +. I have many women (young women I might add), the menopause and HER-2 + tamoxifen and had no recurrence of their cancer. He received Herceptin for 1 year.
I think most oncologists agree that the jury always the possibility of the use of tamoxifen in young women with Her-2-neu-positive, hormone-positive breast cancer. There are theoretical risks of tamoxifen actually increase the risk of recurrence or dissemination, but studies that this risk only just begun and the results are likely years away.
All aromatase inhibitors are associated with arthralgias and myalgias increase to a certain extent. Perhaps your symptoms can be reduced (by switching to non-steroidal AI exemestane). Of course, suppress, with Zoladex estrogen production by the ovaries increases the AI and the elimination of peripheral estrogen production (the relative levels of testosterone, as estrogen decreases). This marked the onset of symptoms in post-menopausal virilization increased, and all that goes with it.
There are a number of over-the-counter means for symptoms such as black cohosh, phytoestrogens, etc.. I warn that your oncologist Befo talkre-test of these methods to help your symptoms. Of course, I think you should be with your oncologist about the necessity of this combination therapy, speech, and ...
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